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15 days ago
Simply Recruitment Partner
Salary band: $10k - $15k
Location: North America, United States, New Hampshire
Job type: Permanent
Contact: Avitide
Category: Engineer
About Avitide

Avitide is a biotechnology company that provides a platform technology to rapidly discover and develop high-performance affinity purification solutions for the biopharmaceutical development and manufacturing industry. Avitide is seeking a qualified candidate to build upon their motivated and highly integrated, interdisciplinary team to pursue the rapid development of novel affinity separation solutions for our biopharmaceutical partners. The Avitide technology enables its partners with exclusive, high-yield, high purity affinity separation technologies that are delivered with an industry-leading service timeline to reduce cost of manufacturing and accelerate the delivery of new medicines to patients.

Avitide's founding team brings substantial expertise and a track record of success in commercializing innovative biopharmaceutical discovery and manufacturing platform technologies. Avitide is financed by top-tier venture capital firms such as Polaris Venture Partners, OrbiMed Advisors, SV Life Sciences, NeoMed Management, and Borealis Ventures.

Avitide is located in New Hampshire's beautiful Upper Connecticut River Valley, and is minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and Dartmouth-Hitchcock Medical Center. The surrounding New Hampshire and Vermont areas are renowned for its premier skiing, hiking, kayaking, and biking. Avitide offers individually tailored compensation packages comprised of competitive salary, bonus, benefits, and equity components.

About This Position

A successful candidate will join Avitide and lead affinity resin development efforts as an integral role the within Avitide's industry-leading affinity purification discovery and development technology. Key responsibilities will include the design, optimization, scouting, and delivery of novel affinity separation matrices to accelerate our partner's biopharmaceutical pipeline. Integrating protein analytics for determining target protein functionality and determining impurity levels is also critical to this function. Avitide seeks candidates who are highly self-motivated and can work in a collaborative fashion with other interdisciplinary team members in a fast-paced company that seeks to transform downstream bioprocessing.Qualifications and Experience:

.Minimum of BS/MS with 4+ years or PhD with 1+ years of industrial experience within a biopharmaceutical bioprocess research and development setting
.Degree (BS/MS/PhD) in biological sciences, biochemistry, or biochemical/chemical engineering
.Expertise in development of protein and biologics purification processes
.Experience with protein quality control or release assays
.Knowledge of biopharmaceutical purification scale-up/scale-down principles
.Demonstrated history of strong hands-on ability, problem solving, and independent experimental design and execution
.Expertise in automated/high-throughput chromatographic screening using DOE methodologies
.Demonstrated aptitude in managing multiple parallel projects
.Timely and very strong communication skills

Duties and Responsibilities:

.Actively contribute to the design, development, optimization, and delivery of novel Avitide affinity resins to Avitide's biopharmaceutical development and manufacturing partners
.Collaborate with downstream bioprocessing engineers at partner companies to streamline technology transfer and integration of Avitide Affinity Resins into partner processes
.High throughput chromatographic screening using DOE and QbD principles
.Purification process development using affinity capture and polish resins, and membranes
.CIP validation and evaluation of protein and column stability
.Work closely with the Affinity Ligand Discovery and High-throughput Production teams to rapidly translate affinity purification leads to affinity resins for partner evaluations
.Preparation of data and presentations for external partner review.

Desirable Skills:

.Experience in biopharmaceutical analytical method development and execution (product purity impurity analysis, product release assays, stability assays)
.Experience with BioSolve or another bioprocess cost modeling software

Avitide Cultural Qualities

.Demonstrate creativity and innovation
.Actively contribute to our collaborative team culture
.Ability to work autonomously and effectively under broad directives
.Agile and quick to adapt
.Excellent and timely communication skills

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